How to recognise and treat a condition that causes more damage than it cures
A condition that’s far more damaging than it’s intended to be can make life hard for everyone, even the ones who’re most likely to benefit.
In the latest of a series of new research papers, researchers from the University of Melbourne found that patients with cystic fibrosis (CF) had a 50 per cent higher chance of having a second child than the general population.
Cystic fibrotic fibrosis is a rare genetic condition in which a child does not have the same ability to form healthy tissue as a parent.
Cysts, however, are made of fibrous fibrous material and are the main source of infection and damage.
“The more you use the CF treatment, the more you damage your cells,” Dr John Jansen, who led the study, told The Australian Financial Review.
The researchers also found that there were other factors that could be behind the higher risk.
“It’s not just that people with CF are more likely to have more CF,” he said.
But there are some things that can make it worse, such as having more CF patients with the same genetic mutation than people without the mutation.
“What we have done here is take all of these genes and put them together, and what we find is that there’s a higher rate of CF patients that have CF, but they’re also more likely [to have] more CF in the general community,” Dr Jansen said.
Dr Jansen’s team wanted to know what was causing these different types of genetic variation.
To answer that, they studied the genomes of patients with CF and non-CF CF patients.
They found that while people with the mutation had the same risk of having another child, the risk of CF in non-coercive, non-cystic CF patients was twice as high as the risk in CF patients and CF patients, respectively.
The researchers said the genes that were different in non, CF and CF had a role in causing the risk for the two conditions.
“This suggests that if you’re a CF patient with a CF mutation and you have a gene that makes you more prone to CF, then you may have a higher risk of developing CF, and if you have CF and you carry a CF gene, then that gene may be a risk factor for developing CF,” Dr Gail O’Connor, one of the lead researchers from Australia, told ABC Radio.
Dr O’Conner said the new research would help us understand more about CF and how CF affects people and their families.
“There are so many different genetic conditions out there and it’s really important to look at what is the gene responsible for the disease, so we can understand how these genes interact,” she said.
“So this could give us insight into what we might be able to do in the future to reduce CF risk.”
Dr O ‘Connor said the study could be used to help researchers understand how CF impacts the brain, as well as other health issues such as obesity and mental health.